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CORSiCA call for Registrations 11/12/2017

We are currently launching the first collaborative research promoted by the European Society of Surgical Oncology Young Alumni Club (EYSAC).

The study entitled Complete Pathologic Response Rectal Cancers EYSAC.1 Study (acronym CORSiCA) will be focused on rectal cancer patients who underwent neoadjuvant treatment and had a final pathologic diagnosis of complete or nearly complete pathologic tumor response in the rectal wall (ypT0) independently from the neoadjuvant /surgical treatment performed or nodal status. Indeed, we aim to create a large Database of ypT0 patients from multiple institutions by involvement of young researchers with a world-wide call for registration.

The study rational is to investigate a large number of ypT0 patients in relation to the nodal status, in order to define their characteristics and to further validate survival outcomes.

The two main hypotheses to test are whether we can distinguish ypT0N0 vs ypT0N+ and if the nodal positivity is a confirmed as an independent variable of survival.

Additionally, we should outline the pattern of recurrences and we will assess the benefits and the compliance that these 2 groups have with adjuvant chemotherapy treatment.

The results of this study would dramatically impact surgical and oncological choices for responders.

The study has a retrospective line of research (last 5 years) and prospectively enrolment (6 months + 2 years of follow-up); each centre will provide a junior (<40 yrs) member for data collection and a senior investigator for data validation. Full protocol has been registered on and it is accessible here.

If you are a young surgical trainee with a special interest in surgical oncology and colorectal surgery aiming to collaborate with your peers we do encourage to register in this study by filling this form.

More information on CORSiCA.

Laura Lorenzon
EYSAC Steering Committee,
Research Delegate,




Karol Polom
EYSAC President,
CORSiCA Member

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